人才队伍学历：博士研究生
学科：高分子化学与物理
电话：0431-85262901
邮箱：clhe@ciac.ac.cn
地址：吉林省长春市人民大街5625号
邮编：130022
1979年12月出生于湖南湘潭。中国科学院长春应用化学研究所研究员，博士生导师。2001年7月毕业于华东理工大学应用化学专业，获工学学士学位;2007年1月毕业于中国科学院长春应用化学研究所高分子化学与物理专业，获理学博士学位。2007年3月至2010年8月，分别在韩国成均馆大学和加拿大渥太华大学从事博士后研究。2010年9月起在中国科学院长春应用化学研究所工作，历任副研究员、研究员。主要从事生物医用高分子水凝胶的研究开发。作为项目负责人先后承担国家自然科学基金5项（包括优秀青年基金、面上和青年基金）。近年来以第一作者或通讯作者发表论文50余篇，申请专利23项，其中授权17项。专业方向为“高分子化学与物理”和“生物化工”。现担任《中国科学：技术科学》和《Science China Technological Sciences》青年编委。2016年获得国家优秀青年科学基金。
1. Zhen Zhang, Chaoliang He*, Yan Rong, Hui Ren, Tianran Wang, Zheng Zou, Xuesi Chen*, A fast and versatile cross-linking strategy via o-phthalaldehyde condensation for mechanically strengthened and functional hydrogels, National Science Review, 7(2020), DOI: 10.1093/nsr/nwaa128.
2. Yuhao Zhou, Liang Liu, Yue Cao, Shuangjiang Yu, Chaoliang He*, Xuesi Chen*, A nanocomposite vehicle based on metal-organic framework nanoparticle incorporated biodegradable microspheres for enhanced oral insulin delivery, ACS Applied Materials & Interfaces, 12(2020), 22581-22592.
3. Shuangjiang Yu, Chao Wang, Jicheng Yu, Jinqiang Wang, Yue Lu, Yuqi Zhang, Xudong Zhang, Quanyin Hu, Wujin Sun, Chaoliang He*, Xuesi Chen*, Zhen Gu*, Injectable bioresponsive gel depot for enhanced immune checkpoint blockade, Advanced Materials, 30(2018), 1801527.
4. Qiang Lv, Chaoliang He*, Fenli Quan, Shuangjiang Yu, Xuesi Chen, DOX/IL-2/IFN-γ co-loaded thermo-sensitive polypeptide hydrogel for efficient melanoma treatment, Bioactive Materials 3(2018), 118-128.
5. Qinghua Xu, Zhen Zhang, Chunsheng Xiao, Chaoliang He*, Xuesi Chen*, Injectable polypeptide hydrogel as biomimetic scaffolds with tunable bioactivity and controllable cell adhesion, Biomacromolecules, 18(2017) , 1411-1418.
6. Chaoliang He, Zhaohui Tang, Huayu Tian, Xuesi Chen*, Co-delivery of chemotherapeutics and proteins for synergistic therapy, Advanced Drug Delivery Reviews, 98(2016), 64-76.
7. Xilong Wu, Chaoliang He*, Yundi Wu, Xuesi Chen*, Synergistic therapeuticeffects of Schiff's base cross-linked injectable hydrogels for local co-delivery of metformin and 5-fluorouracil in a mouse colon carcinoma model, Biomaterials, 75(2016), 148-162.
8. Qinghua Xu, Chaoliang He*, Zhen Zhang, Kaixuan Ren, Xuesi Chen*, Injectable, biomolecule-responsive polypeptide hydrogels for cell encapsulation and facile cell recovery through triggered degradation, ACS Applied Materials & Interfaces, 8(2016), 30692-30702.
9. Qinghua Xu, Chaoliang He*, Chunsheng Xiao, Xuesi Chen*. Reactive oxygen species (ROS) responsive polymers for biomedical applications. Macromolecular Bioscience 2016, 16(5), 635-646.
10. Kaixuan Ren, Chaoliang He*, Chunsheng Xiao, Gao Li*, Xuesi Chen, Injectable glycopolypeptide hydrogels as biomimetic scaffolds for cartilage tissue engineering, Biomaterials, 51(2015), 238-249.
